Nucleosides and Nucleotides

GRK Labs team has extensive experience in sugar/base modifications, scaffold synthesis and phosphonates synthesis. We provide quality products with fast turnaround time and competitive price.

Capabilities

• Modification of base
  • A, U, G, C modifications
  • Metal mediated modification (Suzuki, Stille, Heck, Negishi, Sonogashira and Buchwalrd Amination)
  • C2, C6, C8 of Base modification
  • Fluorination
• Modification of Sugar
  • Deoxy spirocyclic Nucleosides
  • Fluorination
  • Methylation
  • Alkylation
• Synthesis of Nucleoside scaffold/building blocks
• Library synthesis of Nucleoside derivatives
• Acyclic Nucleosides
• Bicyclic and Tricyclic Nucleosides
• Nucleoside Phosphate Esters
• Scale-ups in multi-gram quantities